Pellet Technologies LLC

Naltrexone Pellet Injection Procedure

Naloxone Challenge - 1 mg IV and observe for signs of withdrawal
Administer prophylactic antibiotic
Wash hands with antimicrobial soap
Apply antimicrobial handcream
Apply non-sterile gloves

Cleanse skin with antimicrobial wipe
Cleanse skin with isopropyl alcohol
Local Anesthesia

  Choose a site on the posterolateral aspect of the upper arm.
  Insert a 25 gauge needle at the proximate end of the site and inject 5cc of 2% Lidocaine with Epinephrine and Bicarbonate as the needle is advanced.
  Apply pressure with the syringe so that the hub of the needle causes an indentation to mark the site.
Open packet of sterile supplies
Prepare Area with 3 sterile betadine swabs
Apply sterile gloves
Apply sterile drapes
More Local Anesthesia
  Approximately One half inch distal to the mark left by the hub of the previous injection, inject 5cc of 2% lidocaine with epinephrine and bicarbonate buffer in 5cc syringe with a 18g x 1 ½" needle.
  Advance the needle distally anesthetizing a tract through which to insert the pellet insertion device may be inserted.
Make ~1cm incision with sterile #15 scalpel
Insert the entire sterile pellet insertion device and inject the pellet pellet then withdrawal the device
Close wound with staples from a disposable stapler
Clean wound
Dress wound
  Apply a bandaid.
  Apply a pressure dressing by encircling the upper arm with elastic gauze.
  Dressing to be removed within 12 hours and wound left open.
Provide wound care instruction sheet to patient

This is the simplest method for injecting the pellet which minimizes invasiveness and encourages patient acceptance.

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